Do You Need Virus Neutralization Data for Your Antibodies?
✔ Fast: Get your neutralization data in as little as 4-weeks
✔ Flexible: Probe antibody function with a broad catalog and custom mutations
✔ Expert: A team of virology experts to deliver reliable, cost-effective results

Test Against Any Variant in Our Catalog, and Then Some
Our neutralization assays are functional, cell-based assessments using non-replicative Reporter Virus Particles. A cell-based assay offers insight into the properties of an antibody that impact its clinical usefulness.
We have the tools to immediately assess your antibodies’ neutralizing properties against a wide variety of viruses and strains. Our Reporter Virus catalog is extensive. And we’re continually updating it with the latest SARS-CoV-2 variants of interest, emerging and seasonal influenza strains, as well as additional viruses with high pandemic potential.
If you need antibody neutralization data for a variant not in our catalog, we can make the variant for you—and then run your antibody in an assay.

Popular Applications for Neutralization Assay Services
As a leading service provider for neutralization assays, we do two types of projects. Neutralization Curve projects are for customers who want comparative neutralization data including NT50. Hits projects are a lower-cost option for customers who want to screen a panel of antibody candidates for neutralizing activity.
Applications include the following:Application | Description |
Hit screening | Test a panel of antibodies to identify candidates with neutralizing activity |
Antibody neutralization profiling | Characterize antibody candidates for hit validation or lead selection; test for neutralization against a panel of viral strains |
Breadth of neutralization across viral variants | Test an antibody’s neutralizing ability against multiple viral strains |
Antibody cocktail screening | Test neutralization ability for combinations of antibodies |
Validating predictions | Generate data for molecules predicted by AI or computational modeling that may have virus-neutralizing activity |
Small molecule screening | Test for viral entry inhibition |
Case Study: SARS-CoV-2 Reporter Viruses Reveal Antibodies’ Breadth of Neutralization

Two SARS-CoV-2 MAbs were tested in microneutralization assays for their ability to neutralize Reporter Virus Particles representing six viral variants. Each MAb showed a distinct neutralization profile. Studies like this are useful in SARS therapeutic efficacy testing.
Project Workflow
Before beginning a project, our experts work with you to understand your assay needs and develop a customized statement of work. Once the statement of work is approved, projects generally follow the workflow below.
As part of our commitment to quality, transparency, and timeliness, our team is available throughout the project to answer your questions. Should circumstances arise that could impact the project timeline, we will reach out with updates.

Finding Answers to Your Antibody Questions
Which antibodies in my panel have virus-neutralizing activity?
Which viral variants does my antibody neutralize?
How well does my antibody perform in pseudovirus neutralization assays?
Featured Case Study
Learn how Immunome used SARS-CoV-2 variant RVPs to test their antibody cocktail
Immunome was developing a three-antibody cocktail with broad neutralization potency and a goal of retaining efficacy as the virus evolves. RVPs enabled the team to test their antibody cocktail against a large panel of viral variants of concern.
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Webinar Recording: Innovative Research Tools to Combat Biological Threats
- The use of pseudovirus Reporter Virus Particles (RVPs) in place of live viruses
- How to drive the safe study of new virus variants and mutations of interest
- Why innovative research tools play a critical role in the development of vaccines and treatments for a range of biological threats
- Real-world case studies in discovering and characterizing neutralizing antibodies