In Stock

Zika neutralizing antibody

SKU:
IM-ZKV081
Maximum Purchase:
10 units
Current Stock:
For use with:
Zika RVPs
Unit:
100µg
Applications:
Flow cytometry, Neutralization assay
Lead Time:
Ready to ship
$595.00
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Neutralization experiments were conducted using 5µL of Zika Renilla Luciferase RVPs (INTG Cat # RVP-601L) in a 384-well plate using HEK-293T cells. Renilla luciferase activity measured using the Promega Renilla-Glo luciferase assay system (Promega #E2710). Sample luminescence was read using a Perkin-Elmer Envision plate reader.
Tube of antibody by Integral Molecular, Inc.

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Neutralization experiments were conducted using 5µL of Zika Renilla Luciferase RVPs (INTG Cat # RVP-601L) in a 384-well plate using HEK-293T cells. Renilla luciferase activity measured using the Promega Renilla-Glo luciferase assay system (Promega #E2710). Sample luminescence was read using a Perkin-Elmer Envision plate reader.
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This recombinant monoclonal antibody neutralizes Zika. IM-ZKV081 (LM-081) has been shown to specifically neutralize both live virus and Reporter Virus Particles in cell-based experiments. The specificity of IM-ZKV081 is explained by its epitope, which is unique to Zika amongst flaviviruses, E protein Domain III residue I317. 

Publication describing neutralization and epitope:

Whitbeck JC, Thomas A, Kadash-Edmondson K, et al. Antigenicity, stability, and reproducibility of Zika reporter virus particles for long-term applications. PLoS Negl Trop Dis. 2020;14(11):e0008730. doi:10.1371/journal.pntd.0008730

Product IM-ZKV081, Zika neutralizing antibody (LM-081)
Isotype Human IgG1
Concentration 1 mg/mL
Lead time Ready to ship
Storage conditions Upon receipt, store at 4°C
Size 100 µg (100 µL)

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