Custom Virology Products

Need a custom neutralization assay for your research?

When your neutralization assay calls for a pseudovirus or pseudoinfective viral particle that you can’t find elsewhere, our pseudovirus production experts can make a custom reagent tailored to your exact specifications.

Our custom virology services include

Custom pseudovirus development based on Reporter Virus Particles (RVPs)
Virus-like particle (VLP) services for specialized applications
Custom neutralization assay development and optimization
Target cell line selection

All our virology research services use non-replicative particles that are safe for BSL-2 labs, giving you the flexibility to work with emerging pathogens and rare variants without biosafety concerns.

Frequently requested applications for this service:

Testing vaccines or therapeutic against a potential escape mutation
Measuring breadth of neutralization against variants of interest
Safely studying an emerging, zoonotic, or rare virus

The RVP toolkit includes three core systems: pseudovirus with a lentivirus or VSV core, and pseudoinfective particles built on a flavivirus backbone

RVPs display antigenically correct viral surface proteins and express a convenient optical reporter upon infection. We build RVPs on three non-replicative, BSL-2-safe core systems. You can request a specific system, or we can recommend one or test multiple core systems to optimize your results.

Popular Custom Virology Projects

Our custom virology services adapt to fit your needs—from simple variations of our RVP catalog products, to complex projects involving novel virus-like particles development alongside an optimized assay. Not sure what your project needs? Our virology experts can help you define the scope.

Three categories of custom projects, from simple to complex. 1, making a new variation of an RVP catalog product; 2, making a novel RVP product; and 3, producing a novel RVP product along with a custom assay and cell line.

Project Workflow for Custom Virology Products

Before beginning a project, we will conduct a free, no-obligation analysis of approaches and outcomes for your project. Our scientists will meet with you to discuss feasibility, recommended strategies, and answers to your questions. If you decide to initiate a custom project with us, we will work with you to establish clear and mutually agreeable goals, deliverables, and check-in points.

The typical workflow for a custom RVP project is shown below. More complex projects involving custom assay development and/or nonstandard cell lines include additional development steps, check-in points, and deliverables.

Project deliverables may include the following:

Optimization report
Custom RVPs ready to use in your assays
QC report with infectivity and/or neutralization data
Detailed protocols for any custom assays
Supporting data on target cell line selection or antibody controls

Virology Expertise You Can Trust

The Virology team at Integral Molecular has over a century of combined virology expertise in vector construction, neutralization assays, and related applications. This depth of expertise means:

Faster problem solving when challenges arise
Better recommendations for your specific application
Higher success rates for complex projects
Proven track record with 110+ customer publications and patent citations

Clients appreciate our flexibility and responsiveness. We handle the technical details of assay development details so your team can focus on therapeutic development, assay validation, and advancing your core research.

"Quick and detailed responses to questions and helpful suggestions offered when troubleshooting the assay."

-AN QI NGOH, DUKE-NUS

Custom Pseudovirus & Virus-Like Particle Services to Meet Your Goals

Need a custom neutralization assay for your research?

Popular Custom Virology Projects

Project Workflow for Custom Virology Products

Virology Expertise You Can Trust

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