Integral Molecular’s Zika Reporter Virus Particles (RVPs) are non-replicative, pseudoinfective viral particles that enable safe (BSL-2), easy, and high-throughput viral infectivity and neutralization assays using standard detection instrumentation. The Zika CprME protein is expressed on the surface of the RVP and is designed to have structural and antigenic equivalence to live viruses. The Zika RVPs carry a modified viral minigenome that expresses a luciferase optical reporter gene within 24 hours of cellular infection. Protocols are provided for neutralization and infectivity assays.
Target cells are sold separately.