Integral Molecular’s Yellow Fever Reporter Virus Particles (RVPs) are non-replicative, pseudoinfective viral particles that enable safe (BSL-2), easy, and high-throughput viral infectivity and neutralization assays using standard detection instrumentation. The Yellow Fever prME protein is expressed on the surface of the RVP. The Yellow Fever RVPs carry a modified viral minigenome that expresses a luciferase optical reporter gene within 24 hours of cellular infection. Protocols are provided for neutralization and infectivity assays.
Target cells are sold separately.