Integral Molecular’s Sindbis Virus Reporter Virus Particles (RVPs) are replication-incompetent pseudotyped virus particles that enable safe (BSL-2), easy, and high-throughput viral infectivity and neutralization assays using standard detection instrumentation. The RVPs display the Sindbis Virus envelope protein on a heterologous virus core and carry a modified genome that expresses a convenient optical reporter gene within 24 hours of cellular infection. Protocols are provided for neutralization and infectivity assays and are identical to the CHIKV Reporter Virus Particle documents.
For more details about RVPs, their applications, and answers to frequently asked questions, visit the Reporter Virus Particle Information page. For tips on setting up your own neutralization assay, visit Pseudovirus Neutralization Assays: A How-to Guide for Getting Started.
| Product | Sindbis Virus Reporter Virus Particles (RVPs) |
| Catalog Number | RVP-1116 |
| Strain |
Species exemplar – HRLP, HRSP, AR339, ov-100 Refer to UniProt accession number P03316 |
| Packaging | 20% FBS/DMEM |
| Recommended Input Range | 10uL per well (96-well plate) |
| Target Cell Line | HEK-293T cells |
| Lead time | 1-4 weeks |
| Shipping | Shipped on dry ice |
| Storage conditions | Store at -80°C (+/- 10°C) upon receipt |
| Size | 1.0 mL/vial |
| Warranty | Terms and Conditions (pdf) |
| SDS | Sindbis Virus RVP SDS (pdf) coming soon |
| Protocols | |
| Technical Data Sheets | Sindbis Virus Tech Data Sheet (pdf) |
