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  • Neutralization utilized 5 µl of Marburg RVPs in a 384-well plate. GFP positive cells were detected with an Intellicyt iQue flow cytometer using the BL-1 channel (Ex. 488 nm, Em. 530). Infectivity determined in Huh-7 cells. GFP positive cells were detected with an Intellicyt iQue flow cytometer using the BL-1 channel (Ex. 488 nm, Em. 530).

    Marburg Reporter Virus Particles

    $616.00
    Description Integral Molecular’s Marburg Reporter Virus Particles (RVPs) are replication-incompetent pseudotyped virus particles that enable safe (BSL-2), easy, and high-throughput viral infectivity and neutralization assays using standard...
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  • Neutralization utilized 5 µl of CHIKV RVPs in a 384-well plate with Integral Molecular’s monoclonal antibody (Cat# IMCKV063). GFP positive cells were detected with an Intellicyt iQue flow cytometer using the BL-1 channel (Ex. 488 nm, Em. 530). Infectivity determined in HEK-293T cells. Infectivity data represents the average of three independent vials, each tested in quadruplicate.

    Chikungunya Reporter Virus Particles

    $616.00
    Description Integral Molecular’s Chikungunya Reporter Virus Particles (RVPs) are replication-incompetent pseudotyped virus particles that enable safe (BSL-2), easy, and high-throughput viral infectivity and neutralization assays using standard...
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  • Infectivity is determined in HEK-293T cells. Data are based on three independent tubes, each tested in quadruplicate. GFP positive cells were detected with an Intellicyt iQue flow cytometer. Increasing infectity is seen with increasing inputs of pseudovirus as expected. VSV with MLV RVPs can be used as a neutralization control with our transgenic ACE2 cells

    VSV Reporter Virus Particles with MLV core

    $616.00
    Description Integral Molecular’s VSV Reporter Virus Particles (RVPs) function as a control for RVP experiments to differentiate specific versus non-specific effects on neutralization. VSV RVPs are replication-incompetent pseudotyped virus...
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  • Flow cytometry analysis of BHK DC-SIGN cells (Cat# C-BD101) with a DC-SIGN specific monoclonal antibody (R&D Systems Cat# MAB161). Detection using a secondary antibody labelled with AlexaFluor 488 (Jackson ImmunoResearch Cat# 115-545-003). Fluorescence was detected with an Intellicyt iQue flow cytometer using the BL-1 channel (Ex. 488 nm, Em. 530). Vials of cells by Integral Molecular, Inc.

    BHK DC-SIGN Stable Cell Line

    $1,725.00
    Description The BHK DC-SIGN monoclonal cell line was generated using baby hamster kidney (BHK) cells to create a permissive cell line for efficient infection by flavivirus Reporter Virus Particles.  The cells were developed from BHK21 clone 15...
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  • Neutralization (using monoclonal antibody 4G2) utilized 5 µl of DENV RVPs in a 96-well plate. Renilla luciferase activity measured using the Promega Renilla luciferase assay system (Promega #E2810). Sample luminescence was read using a Perkin-Elmer Envision plate reader. Infectivity determined in BHK DC-SIGN cells (Cat# C-BD101).

    Dengue Serotype 1 Reporter Virus Particles

    $616.00
    Description Integral Molecular’s Dengue-1 Reporter Virus Particles (RVPs) are non-replicative, pseudoinfective viral particles that enable safe (BSL-2), easy, and high-throughput viral infectivity and neutralization assays using standard...
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  • HAI assay was performed using 1% Guinea Pig RBCs in a 96-well plate. The titer at 4 HA units and hyperimmune serum were used to perform the HAI assay. Reported serum dilutions are defined prior to TiterSafe volume addition. HAI assay was performed using 1% Guinea Pig RBCs in a 96-well plate. The titer at 4 HA units and hyperimmune serum were used to perform the HAI assay. Reported serum dilutions are defined prior to TiterSafe volume addition.

    TiterSafe Influenza B (Victoria)

    $755.00
    Description Influenza TiterSafe, an HAI reagent, consists of non-replicative virus-like particles (VLPs) that display influenza HA and NA on a lentivirus core. TiterSafe replaces live virus in the hemagglutination inhibition assay (HAI), the standard...
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  • Neutralization experiments were conducted using 5µL of SARS-CoV-2 RVPs (Omicron BA.1, Cat # RVP-768G; Omicron BA.2, Cat # RVP-770G; Omicron BA.2.75, Cat # RVP-776G; Delta, Cat # RVP-763G; D614G, Cat # RVP-702G) in a 384-well plate using HEK-293T monoclonal cells stably overexpressing ACE2 (Cat # CHA102). Tube of antibody by Integral Molecular, Inc.

    SARS-CoV-2 Broadly Neutralizing Antibody (including first-generation Omicron variants)

    $595.00
    Description This recombinant monoclonal antibody neutralizes SARS-CoV-2 variants including Wuhan-Hu-1, D614G, Alpha, and Omicron variants BA.1, BA.1.1, and BA.2. This clone weakly neutralizes Omicron variant BA.2.75 and does not neutralize Omicron...
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  • Flow cytometry analysis of 293T-hsACE2 cells (Cat# C-HA102) with an ACE2 specific monoclonal antibody (R&D Systems Cat# MAB9332-100). Detection using a secondary antibody labelled with AlexaFluor 488 (Jackson ImmunoResearch Cat# 115-545-003). Fluorescence was detected with an Intellicyt iQue flow cytometer using the BL-1 channel (Ex. 488 nm, Em. 530). Vials of cells by Integral Molecular, Inc.

    293T-hsACE2 Clonal Cell Line

    $1,725.00
    Description For your best signal in SARS-CoV-2 neutralization or infectivity assays, use our 293T-hsACE2 monoclonal cell line. This HEK-293T human embryonic kidney cells overexpresses human angiotensin-converting enzyme 2 (hACE2, GenBank Accession#...
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  • Neutralization utilized 5 µl of SARS-CoV-2 RVPs in a 384-well plate. GFP positive cells were detected with an Intellicyt iQue flow cytometer using the BL-1 channel (Ex. 488 nm, Em. 530). Infectivity and neutralization determined in HEK-293T cells stably over-expressing ACE2 (Integral Cat# C-HA102). Infectivity data represents the average of three independent vials, each tested in quadruplicate.

    SARS-CoV-2 D614G Reporter Virus Particles

    $616.00
    Description Integral Molecular’s SARS-CoV-2 Reporter Virus Particles (RVPs) are replication-incompetent pseudotyped virus particles that enable safe (BSL-2), easy, and high-throughput viral infectivity and neutralization assays using standard...
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  • Neutralization utilized 5 µl of SARS-CoV-2 RVPs in a 384-well plate. GFP positive cells were detected with an Intellicyt iQue flow cytometer using the BL-1 channel (Ex. 488 nm, Em. 530). Infectivity and neutralization determined in HEK-293T cells stably over-expressing ACE2 (Integral Cat# C-HA102). Infectivity data represents the average of three independent vials, each tested in quadruplicate.

    SARS-CoV-2 Wuhan-Hu-1 Reporter Virus Particles

    $616.00
    Description Integral Molecular’s SARS-CoV-2 Reporter Virus Particles (RVPs) are replication-incompetent pseudotyped virus particles that enable safe (BSL-2), easy, and high-throughput viral infectivity and neutralization assays using standard...
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