Products to use with RVPs

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  • Neutralization experiments were conducted using 5µL of Zika Renilla Luciferase RVPs (INTG Cat # RVP-601L) in a 384-well plate using HEK-293T cells. Renilla luciferase activity measured using the Promega Renilla-Glo luciferase assay system (Promega #E2710). Sample luminescence was read using a Perkin-Elmer Envision plate reader. Tube of antibody by Integral Molecular, Inc.

    Zika neutralizing antibody

    $595.00
    Description This recombinant monoclonal antibody neutralizes Zika. IM-ZKV081 (LM-081) has been shown to specifically neutralize both live virus and Reporter Virus Particles in cell-based experiments. The specificity of IM-ZKV081 is explained by its...
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  • Neutralization experiments were conducted using 5µL of CHIKV GFP RVPs (INTG Cat # RVP 1101G) in a 384-well plate using HEK-293T cells. Tube of antibody by Integral Molecular, Inc.

    Chikungunya neutralizing antibody

    $595.00
    Description This recombinant monoclonal antibody neutralizes Chikungunya. The antibody sequence was recovered from an individual who was infected and recovered from CHIKV during the 2006 outbreak in La Réunion, France. The antibody epitope is...
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  • Neutralization experiments were conducted using 5µL of SARS-CoV-2 RVPs (Omicron BA.1, INTG Cat # RVP 768G; Omicron BA.2, INTG Cat # RVP 770G; Omicron BA.2.75, INTG Cat # RVP 776G; Delta, INTG Cat # RVP 763G; D614G, INTG Cat # RVP 702G) in a 384-well plate using HEK-293T monoclonal cells stably overexpressing ACE2 (INTG Cat # CHA102). Tube of antibody by Integral Molecular, Inc.

    SARS-CoV-2 Broadly Neutralizing Antibody (including Delta)

    $595.00
    Description This recombinant monoclonal antibody neutralizes SARS-CoV-2 variants including Wuhan-Hu-1, D614G, Alpha, and Delta. This clone weakly neutralizes Omicron variant s BA.1 and BA.1.1.  Product IM-CoV2-G06, SARS-CoV-2 broadly...
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  • Infectivity is determined in HEK-293T cells. Data are based on three independent tubes, each tested in quadruplicate. GFP positive cells were detected with an Intellicyt iQue flow cytometer. Increasing infectity is seen with increasing inputs of pseudovirus as expected. VSV with MLV RVPs can be used as a neutralization control with our transgenic ACE2 cells

    VSV Reporter Virus Particles with MLV core

    $616.00
    Description Integral Molecular’s VSV Reporter Virus Particles (RVPs) function as a control for RVP experiments to differentiate specific versus non-specific effects on neutralization. VSV RVPs are replication-incompetent pseudotyped virus...
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  • Flow cytometry analysis of BHK DC-SIGN cells (Cat# C-BD101) with a DC-SIGN specific monoclonal antibody (R&D Systems Cat# MAB161). Detection using a secondary antibody labelled with AlexaFluor 488 (Jackson ImmunoResearch Cat# 115-545-003). Fluorescence was detected with an Intellicyt iQue flow cytometer using the BL-1 channel (Ex. 488 nm, Em. 530). Vials of cells by Integral Molecular, Inc.

    BHK DC-SIGN Stable Cell Line

    $1,725.00
    Description The BHK DC-SIGN monoclonal cell line was generated using baby hamster kidney (BHK) cells to create a permissive cell line for efficient infection by flavivirus Reporter Virus Particles.  The cells were developed from BHK21 clone 15...
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  • Neutralization experiments were conducted using 5µL of SARS-CoV-2 RVPs (Omicron BA.1, Cat # RVP-768G; Omicron BA.2, Cat # RVP-770G; Omicron BA.2.75, Cat # RVP-776G; Delta, Cat # RVP-763G; D614G, Cat # RVP-702G) in a 384-well plate using HEK-293T monoclonal cells stably overexpressing ACE2 (Cat # CHA102). Tube of antibody by Integral Molecular, Inc.

    SARS-CoV-2 Broadly Neutralizing Antibody (including first-generation Omicron variants)

    $595.00
    Description This recombinant monoclonal antibody neutralizes SARS-CoV-2 variants including Wuhan-Hu-1, D614G, Alpha, and Omicron variants BA.1, BA.1.1, and BA.2. This clone weakly neutralizes Omicron variant BA.2.75 and does not neutralize Omicron...
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  • Flow cytometry analysis of 293T-hsACE2 cells (Cat# C-HA102) with an ACE2 specific monoclonal antibody (R&D Systems Cat# MAB9332-100). Detection using a secondary antibody labelled with AlexaFluor 488 (Jackson ImmunoResearch Cat# 115-545-003). Fluorescence was detected with an Intellicyt iQue flow cytometer using the BL-1 channel (Ex. 488 nm, Em. 530). Vials of cells by Integral Molecular, Inc.

    293T-hsACE2 Clonal Cell Line

    $1,725.00
    Description For your best signal in SARS-CoV-2 neutralization or infectivity assays, use our 293T-hsACE2 monoclonal cell line. This HEK-293T human embryonic kidney cells overexpresses human angiotensin-converting enzyme 2 (hACE2, GenBank Accession#...
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