Integral Molecular’s Human Immunodeficiency Virus (HIV) Reporter Virus Particles (RVPs) are replication-incompetent pseudotyped virus particles that enable safe (BSL-2), easy, and high-throughput viral infectivity and neutralization assays using standard detection instrumentation. The RVPs display the HIV envelope proteins on a heterologous virus core and carry a modified genome that expresses a convenient optical reporter gene within 24 hours of cellular infection. Protocols are provided for neutralization and infectivity assays.
For more details about RVPs, their applications, and answers to frequently asked questions, visit the Reporter Virus Particle Information page. For tips on setting up your own neutralization assay, visit Pseudovirus Neutralization Assays: A How-to Guide for Getting Started.
| Product | HIV Reporter Virus Particles (RVPs) |
| Catalog Number | RVP-2000 |
| Strain | B41 |
| Packaging | 20% FBS/DMEM |
| Recommended Input Range | 2.5μL per well (96-well plate) for ~20% infectivity in a flow assay* |
| Viral Titer | 3.23 x 106 TU/ml |
* Determined in the U87 CD4/CCR5 cell line
| Lead time | 1-4 weeks |
| Shipping | Shipped on dry ice |
| Storage conditions | Store at -80°C (+/- 10°C) upon receipt |
| Size | 1.0 mL/vial |
| Warranty | Terms and Conditions (pdf) |
| SDS | HIV RVP SDS (pdf) |
| Protocols | |
| Technical Data Sheets | HIV RVP Tech Data Sheets |
