Integral Molecular’s Dengue-4 Reporter Virus Particles (RVPs) are non-replicative, pseudoinfective viral particles that enable safe (BSL-2), easy, and high-throughput viral infectivity and neutralization assays using standard detection instrumentation. The dengue-4 prME protein is expressed on the surface of the RVP and is designed to have structural and antigenic equivalence to live viruses. The dengue-4 RVPs carry a modified viral minigenome that expresses a luciferase optical reporter gene within 24 hours of cellular infection. Protocols are provided for neutralization and infectivity assays.
Target cells are sold separately.
