Integral Molecular’s VSV Reporter Virus Particles (RVPs) function as a control for RVP experiments to differentiate specific versus non-specific effects on neutralization. VSV RVPs are replication-incompetent pseudotyped virus particles that enable easy, high-throughput viral infectivity and neutralization assays using standard detection instrumentation. The RVPs display VSV-G on a heterologous lentiviral virus core and carry a modified genome that expresses a convenient optical reporter gene within 24 hours of cellular infection. Protocols are provided for neutralization and infectivity assays.
VSV has a broad tropism and is compatible for use with nearly all target cells including ACE2-HEK-293T
For more details about RVPs, their applications, and answers to frequently asked questions, visit the Reporter Virus Particle Information page. For tips on setting up your own neutralization assay, visit Pseudovirus Neutralization Assays: A How-to Guide for Getting Started.
| Product | VSV with MLV core Reporter Virus Particles (RVPs) |
| Catalog Number | RVP-1002 |
| Strain | Indiana |
| Recommended Input Range | 3-8 uL per well (96-well plate) |
| Lead time | 1-4 weeks |
| Shipping | Shipped on dry ice |
| Storage conditions | Store at -80°C (+/- 10°C) upon receipt |
| Size | 1.0 mL/vial |
