Integral Molecular’s Dengue-1 Reporter Virus Particles (RVPs) are non-replicative, pseudoinfective viral particles that enable safe (BSL-2), easy, and high-throughput viral infectivity and neutralization assays using standard detection instrumentation. The dengue-1 prME protein is expressed on the surface of the RVP and is designed to have structural and antigenic equivalence to live viruses. The dengue-1 RVPs carry a modified viral minigenome that expresses a luciferase optical reporter gene within 24 hours of cellular infection. Protocols are provided for neutralization and infectivity assays.
Target cells are sold separately.
For more details about RVPs, their applications, and answers to frequently asked questions, visit the Reporter Virus Particle Information page. For tips on setting up your own neutralization assay, visit Pseudovirus Neutralization Assays: A How-to Guide for Getting Started.
| Product | Dengue 1 Reporter Virus Particles (RVPs) |
| Catalog Number | RVP-101 |
| Strain | Dengue Serotype 1 (16007) |
| Packaging | 20% FBS/DMEM |
| Recommended Input Range | 1 uL per well (96-well plate) |
| Target Cell Line | BHK cells, DC-SIGN stable cell line (Cat# C-BD102) |
| Lead time | Ready to ship |
| Shipping | Shipped on dry ice |
| Storage conditions | Store at -80°C (+/- 10°C) upon receipt |
| Size | 1.0 mL/vial |
| Warranty | Terms and Conditions (pdf) |
| SDS | Dengue 1 RVP SDS (pdf) |
| Protocols | |
| Technical Data Sheets | Dengue Tech Data Sheets |
