Integral Molecular’s Bundibugyo Ebolavirus Reporter Virus Particles (RVPs) are replication-incompetent pseudotyped virus particles that enable safe (BSL-2), easy, and high-throughput viral infectivity and neutralization assays using standard detection instrumentation. Without the hassle of BSL-4 containment, filovirus RVPs enable more accessible assays in response to outbreaks and new threats. The RVPs display ebolavirus glycoprotein based on the isolate from the 2026 outbreak in the Democratic Republic of the Congo [accession ID: PP_006XHL9.2] on a VSV core and carry a modified genome that expresses a convenient optical reporter gene within 24 hours of cellular infection. Protocols are provided for neutralization and infectivity assays.
For more details about RVPs, their applications, and answers to frequently asked questions, visit the Reporter Virus Particle Information page. For tips on setting up your own neutralization assay, visit Pseudovirus Neutralization Assays: A How-to Guide for Getting Started.
Looking for the 2007 outbreak isolate for Bundibugyo instead? RVPs will be available soon for BDBV/H.sapiens-tc/UGA/2007/Butalya-811250.
| Product | Bundibugyo Ebola Reporter Virus Particles (RVPs) |
| Catalog Number | RVP-1426 |
| Strain | Democratic_Republic_of_the_Congo/PP_006XHL9.2/2026-05-07 |
| Accession ID | PP_006XHL9.2 |
| Packaging | 20% FBS/DMEM |
| Recommended Input Range | TBD μL per well (96-well plate) for ~20% infectivity in a flow assay |
| Viral Titer | TBD TU/ml |
| Target Cell Line | TBD |
| Lead time | Coming soon! |
| Shipping | Shipped on dry ice |
| Storage conditions | Store at -80°C (+/- 10°C) upon receipt |
| Size | 1.0 mL/vial |
| Warranty | Terms and Conditions (pdf) |
| SDS | Ebola RVP SDS (pdf) |
| Protocols | |
| Technical Data Sheets | RVP Tech Data Sheets |
